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Cannabicyclohexanol

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Chemical Overview: Cannabicyclohexanol (CCH)

Type: Synthetic cannabinoid receptor agonist (mimics THC)

Chemical family: 1,1-dimethyloctyl homologue of CP 47,497

Discovery: Developed by Pfizer in 1979

Use in “Spice” products: Main active ingredient in herbal incense products like Spice around 2009

Chemical formula: C22H36O2 | Molar mass: 332.53 g/mol

Enantiomers: Four enantiomers; potency varies significantly; most samples contain a mixture

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Cannabicyclohexanol (CCH): Description & Educational Information

Description

CCH is a synthetic cannabinoid designed to activate the same brain receptors as THC. It was first developed by Pfizer in 1979 and later became a major component of “Spice” herbal incense products. Unlike natural cannabis, its effects are less predictable and often stronger.

Pharmacology

CCH binds to cannabinoid receptors (CB1 and CB2) in the central nervous system. The 1,1-dimethyloctyl version is several times more potent than its parent compound CP 47,497. Different enantiomers contribute to variable potency and effect profiles.

Effects

Users may experience cannabis-like effects, including relaxation and euphoria. However, effects are often more intense and unpredictable due to the synthetic nature and enantiomer mix.

Risks

Reported health risks include heart problems, seizures, psychosis, extreme agitation, and poisoning. Effects may vary widely depending on concentration and isomer composition.

Legal & Safety

CCH is considered a controlled substance or illegal in many countries due to its unpredictable potency and associated health risks. Use in unregulated herbal products carries significant safety concerns.

Contact Information

For safety or health inquiries, consult national poison control centers or public health authorities.

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